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Nature of Business (Details) (USD $)
2 Months Ended 1 Months Ended
Mar. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Mar. 31, 2014
Series B-2 Shares
Feb. 14, 2014
Series B-2 Shares
Dec. 31, 2013
Series B-2 Shares
Mar. 31, 2014
Series B-2 Shares
Maximum
Feb. 14, 2014
Series B-2 Shares
Maximum
Mar. 31, 2014
Series B-2 Purchase Agreement
Subsequent Event
Feb. 14, 2014
Series B-2 Purchase Agreement
Subsequent Event
Feb. 14, 2014
Series B-2 Purchase Agreement
Maximum
Subsequent Event
Mar. 31, 2014
Series B-2 Purchase Agreement
Series B-2 Shares
Subsequent Event
Feb. 14, 2014
Series B-2 Purchase Agreement
Series B-2 Shares
Maximum
Subsequent Event
Organization                          
Accumulated deficit $ 296,247,000 $ 277,301,000 $ 200,661,000                    
Convertible Preferred Stock                          
Amount to be raised               40,200,000     40,200,000    
Preferred Stock, shares authorized       655,000   655,000   655,000         655,000
Warrants that may be issued for purchase of shares of common stock (in shares)               718,201     718,201    
Exercise price of warrants (in dollars per unit)         $ 14.004         $ 14.004      
Proceeds from issuance of shares       $ 27,500,000         $ 27,500,000        
Number of shares issued       448,060   0           448,060  
Warrants issued for purchase of shares of common stock (in shares)             491,293   491,293