X0306 4/A 2020-06-15 2020-06-15 0 0001427925 ACELRX PHARMACEUTICALS INC ACRX 0001248144 ADAMS ADRIAN C/O ACELRX PHARMACEUTICALS, INC. 351 GALVESTON DRIVE REDWOOD CITY CA 94063 1 0 0 0 Common Stock 2020-06-15 4 P 0 100000 1.289 A 178750 D The price reported on Column 4 is a weighted average price. These shares were purchased in multiple transactions ranging from $1.27 to $1.30 on June 15, 2020. The reporting person will provide upon request to the SEC, the issuer or security holder of Issuer, full information regarding the number of shares purchased at each separate price. /s/ Martha Adler, Attorney-In-Fact 2020-06-15