INCOME TAXES - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Millions	Dec. 31, 2024	Dec. 31, 2023
Deferred tax assets
Foreign net operating loss and other carryforwards	$ 1,521	$ 2,017
State net operating loss and credit carryforwards	529	349
U.S. Federal capital loss, net operating loss and tax credit	695	249
Milestone payments and license fees	999	918
Capitalized research expenditures	3,886	2,682
Other	1,738	1,883
Total deferred tax assets	9,368	8,098
Valuation allowance	(929)	(764)
Deferred tax assets net of valuation allowance	8,439	7,334
Deferred tax liabilities
Acquired intangible assets	(3,781)	(4,052)
Goodwill and other	(791)	(852)
Total deferred tax liabilities	(4,572)	(4,904)
Deferred tax assets/(liabilities), net	3,867	2,430
Deferred income taxes assets – non-current	4,236	2,768
Deferred income taxes liabilities – non-current	$ (369)	$ (338)