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ACQUISITIONS, DIVESTITURES, LICENSING AND OTHER ARRANGEMENTS - Narrative (Details)
$ / shares in Units, $ in Millions
1 Months Ended 12 Months Ended 24 Months Ended
Mar. 18, 2024
USD ($)
$ / shares
Feb. 26, 2024
USD ($)
$ / shares
Jan. 23, 2024
USD ($)
Jan. 31, 2024
USD ($)
right
$ / shares
Oct. 31, 2023
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2014
Dec. 31, 2026
Feb. 28, 2025
USD ($)
Jan. 31, 2025
USD ($)
Business Acquisition [Line Items]                        
Royalty Income           $ 1,104 $ 862 $ 832        
Keytruda Royalties                        
Business Acquisition [Line Items]                        
Percentage of net sales payable to alliance partner           2.50% 6.50%          
LianBio Co. Ltd. | Mavacamten Rights                        
Business Acquisition [Line Items]                        
Payments for asset acquisitions         $ 445              
Payments to acquire rights         $ 350              
Bristol-Myers Squibb | Keytruda Royalties | Forecast | Subsequent Event                        
Business Acquisition [Line Items]                        
Payment and royalty allocation                   75.00%    
Ono | Keytruda Royalties | Forecast | Subsequent Event                        
Business Acquisition [Line Items]                        
Payment and royalty allocation                   25.00%    
Immatics                        
Business Acquisition [Line Items]                        
License and other arrangements upfront payments               150        
Dragonfly                        
Business Acquisition [Line Items]                        
License and other arrangements upfront payments               175        
BioArctic | Forecast                        
Business Acquisition [Line Items]                        
License and other arrangements upfront payments                       $ 100
Contingent and regulatory milestone payments                     $ 1,300  
Mavacamten                        
Business Acquisition [Line Items]                        
Payment to extinguish future royalty obligation               295        
Diabetes business - royalties                        
Business Acquisition [Line Items]                        
Royalty Income           $ 1,097 $ 862 810        
Diabetes business - royalties | Supply Agreements                        
Business Acquisition [Line Items]                        
Royalty Income           1,200 960 924        
Diabetes business - royalties | Amylin, Onglyza, and Farxiga                        
Business Acquisition [Line Items]                        
Business sale royalty expense           96 98 114        
Mature products and other                        
Business Acquisition [Line Items]                        
Royalty Income           7 0 $ 22        
Minimum | Diabetes business - royalties                        
Business Acquisition [Line Items]                        
Percentage of net sales payable to alliance partner                 10.00%      
Maximum | Diabetes business - royalties                        
Business Acquisition [Line Items]                        
Percentage of net sales payable to alliance partner                 25.00%      
Orum                        
Business Acquisition [Line Items]                        
Payments for asset acquisitions             100          
Asset acquisition, consideration transferred, contingent consideration             80          
Karuna                        
Business Acquisition [Line Items]                        
Asset acquisition, share price (in dollars per share) | $ / shares $ 330.00                      
Payments for asset acquisitions $ 14,027                      
Payments for asset acquisitions, net of cash acquired $ 12,900                      
Karuna | Acquired IPRD                        
Business Acquisition [Line Items]                        
Payments for asset acquisitions           $ 12,100            
RayzeBio                        
Business Acquisition [Line Items]                        
Business acquisition, share price (in usd per share) | $ / shares   $ 62.50                    
Acquisitions (Note 4)   $ 4,147                    
Total consideration allocated   3,600                    
Intangible assets   3,700                    
RayzeBio | In Process Research and Development                        
Business Acquisition [Line Items]                        
Identifiable assets acquired, indefinite-lived intangible assets   1,700                    
RayzeBio | Developed Technology Rights                        
Business Acquisition [Line Items]                        
Identifiable assets acquired, indefinite-lived intangible assets   $ 2,000                    
Mirati Therapeutics                        
Business Acquisition [Line Items]                        
Business acquisition, share price (in usd per share) | $ / shares       $ 58.00                
Acquisitions (Note 4)     $ 4,801 $ 4,800                
Total consideration allocated     4,100                  
Business combination, contingent value, number of rights received | right       1                
Business combination, contingent value, share price (in dollars per share) | $ / shares       $ 12.00                
Contingent consideration liability       $ 1,000                
Business combination, contingent value payout, period       7 years                
Inventories     215                  
Intangible assets     4,225                  
Mirati Therapeutics | In Process Research and Development                        
Business Acquisition [Line Items]                        
Intangible assets     3,500                  
Mirati Therapeutics | Acquired Marketed Product Rights                        
Business Acquisition [Line Items]                        
Intangible assets     640                  
Turning Point                        
Business Acquisition [Line Items]                        
Acquisitions (Note 4)             4,100          
Total consideration allocated             $ 3,300          
Inventory Purchase Price Fair Value Adjustment                        
Business Acquisition [Line Items]                        
Inventories     $ 148