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ACQUISITIONS, DIVESTITURES, LICENSING AND OTHER ARRANGEMENTS - Divestitures (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Divestiture proceeds $ 1,157 $ 748 $ 715
Divestiture gains (Note 4) (211) (9) (55)
Royalty Income (832) (666) (644)
Diabetes business      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Divestiture proceeds 767 612 558
Divestiture gains (Note 4) 0 0 0
Royalty Income (810) (622) (567)
Mature products and other      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Divestiture proceeds 390 136 157
Divestiture gains (Note 4) (211) (9) (55)
Royalty Income (22) (44) (77)
Not all inclusive      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]      
Divestiture gains (Note 4) $ (211) $ (9) $ (55)