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ACQUISITIONS, DIVESTITURES, LICENSING AND OTHER ARRANGEMENTS - Additional Information (Details) - USD ($)
$ in Millions
1 Months Ended 12 Months Ended 36 Months Ended 84 Months Ended
Feb. 14, 2023
Feb. 28, 2014
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2026
Dec. 31, 2023
Jan. 31, 2023
Mar. 31, 2022
Nov. 30, 2020
Business Acquisition [Line Items]                    
Acquired IPRD     $ 815 $ 1,159 $ 12,533          
Marketing, selling and administrative     7,814 7,690 7,661          
Research and development     9,509 10,195 10,048          
Royalty Income     832 666 644          
Proceeds from divestiture of businesses, net of cash divested     1,157 748 715          
Divestiture gain     211 9 55          
Turning Point                    
Business Acquisition [Line Items]                    
Payments to acquire businesses, gross     4,113              
Acquisition, net of cash acquired     3,300              
Keytruda Royalties | Forecast                    
Business Acquisition [Line Items]                    
Percentage of net sales payable to alliance partner             6.50%      
Keytruda Royalties | Subsequent Event | Forecast                    
Business Acquisition [Line Items]                    
Percentage of net sales payable to alliance partner           2.50%        
Tecentriq Royalties                    
Business Acquisition [Line Items]                    
Proceeds from out-licensed arrangements       324            
Patent settlement income       239            
Dragonfly                    
Business Acquisition [Line Items]                    
Upfront payments for licensing and alliance arrangements         475          
Payment for additional targets made to collaborative partner         75          
Collaborative arrangement contingent payments maximum exposure         2,700          
Dragonfly | Subsequent Event                    
Business Acquisition [Line Items]                    
Termination of license               90 days    
Nimbus Therapuetics TYK2 Inhibitor                    
Business Acquisition [Line Items]                    
Income from settlement     40              
Nimbus Therapuetics TYK2 Inhibitor | Subsequent Event                    
Business Acquisition [Line Items]                    
Collaborative arrangement contingent payments maximum exposure $ 2,000                  
Mavacamten                    
Business Acquisition [Line Items]                    
Payment to extinguish future royalty obligation     (295)              
Diabetes business                    
Business Acquisition [Line Items]                    
Royalty Income     810 622 567          
Proceeds from divestiture of businesses, net of cash divested     767 612 558          
Divestiture gain     0 0 0          
Diabetes business | Minimum                    
Business Acquisition [Line Items]                    
Percentage of net sales payable to alliance partner   10.00%                
Diabetes business | Maximum                    
Business Acquisition [Line Items]                    
Percentage of net sales payable to alliance partner   25.00%                
Diabetes business | Supply Agreements                    
Business Acquisition [Line Items]                    
Royalty Income     924 725 673          
Diabetes business | Amelyn, Onglyza, and Farxiga                    
Business Acquisition [Line Items]                    
Business sale royalty expense     114 103 106          
Mature Brands and Other                    
Business Acquisition [Line Items]                    
Divestiture gain     211              
Mature Brands and Other | Discontinued Operations, Held-for-sale                    
Business Acquisition [Line Items]                    
Assets held for sale     172              
Liabilities held for sale     20              
Mature Brands and Other | Cost of products sold                    
Business Acquisition [Line Items]                    
Asset impairment charges     63              
Mature brand, Teofarma                    
Business Acquisition [Line Items]                    
Proceeds from divestiture of businesses, net of cash divested       50            
Divestiture gain       49            
LOTTE Corporation | Mature Brands and Other                    
Business Acquisition [Line Items]                    
Sales price     159              
Immatics                    
Business Acquisition [Line Items]                    
Contingent and regulatory milestone payments     770              
License and other arrangements upfront payments                 $ 150  
Dragonfly                    
Business Acquisition [Line Items]                    
License and other arrangements upfront payments     (175)              
Agenus                    
Business Acquisition [Line Items]                    
Contingent and regulatory milestone payments       1,400            
License and other arrangements upfront payments       $ 200            
Cheplapharm | Mature Brands and Other                    
Business Acquisition [Line Items]                    
Proceeds from divestiture of businesses, net of cash divested     $ 221              
MyoKardia Acquisition                    
Business Acquisition [Line Items]                    
Consideration paid                   $ 13,100
Acquired IPRD         11,400          
Assets assumed         1,400          
Liabilities assumed         226          
Unvested stock awards expensed to marketing, selling and administrative expense and research and development         482          
Marketing, selling and administrative         241          
Research and development         241          
Forbius                    
Business Acquisition [Line Items]                    
Consideration paid         185          
Contingent and regulatory milestone payments         815          
Upfront payment, acquired IPRD         178          
Deferred income taxes acquired through an asset acquisition         $ 7          
Bristol-Myers Squibb | Keytruda Royalties | Subsequent Event | Forecast                    
Business Acquisition [Line Items]                    
Payment and royalty allocation           75.00%        
Ono | Keytruda Royalties | Subsequent Event | Forecast                    
Business Acquisition [Line Items]                    
Payment and royalty allocation           25.00%        
Nimbus Therapeutics | Subsequent Event                    
Business Acquisition [Line Items]                    
License and other arrangements upfront payments $ 4,000                  
Nimbus Therapeutics | Nimbus Therapuetics TYK2 Inhibitor                    
Business Acquisition [Line Items]                    
Change in control proceeds     10.00%              
Nimbus Therapeutics | Nimbus Therapuetics TYK2 Inhibitor | Subsequent Event                    
Business Acquisition [Line Items]                    
Percentage of ownership acquired 100.00%