REVENUE - Disaggregation of Revenue by Product and Region (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenue from External Customer [Line Items]
Total Revenues	$ 46,159	$ 46,385	$ 42,518
United States
Revenue from External Customer [Line Items]
Total Revenues	31,828	29,214	26,577
International
Revenue from External Customer [Line Items]
Total Revenues	13,497	16,319	15,310
Other
Revenue from External Customer [Line Items]
Total Revenues	834	852	631
Eliquis
Revenue from External Customer [Line Items]
Total Revenues	11,789	10,762	9,168
Opdivo
Revenue from External Customer [Line Items]
Total Revenues	8,249	7,523	6,992
Pomalyst/Imnovid
Revenue from External Customer [Line Items]
Total Revenues	3,497	3,332	3,070
Orencia
Revenue from External Customer [Line Items]
Total Revenues	3,464	3,306	3,157
Sprycel
Revenue from External Customer [Line Items]
Total Revenues	2,165	2,117	2,140
Yervoy
Revenue from External Customer [Line Items]
Total Revenues	2,131	2,026	1,682
Empliciti
Revenue from External Customer [Line Items]
Total Revenues	296	334	381
Mature and other brands
Revenue from External Customer [Line Items]
Total Revenues	1,749	1,900	2,217
Reblozyl
Revenue from External Customer [Line Items]
Total Revenues	717	551	274
Abecma
Revenue from External Customer [Line Items]
Total Revenues	388	164	0
Opdualag
Revenue from External Customer [Line Items]
Total Revenues	252	0	0
Zeposia
Revenue from External Customer [Line Items]
Total Revenues	250	134	12
Breyanzi
Revenue from External Customer [Line Items]
Total Revenues	182	87	0
Onureg
Revenue from External Customer [Line Items]
Total Revenues	124	73	17
Inrebic
Revenue from External Customer [Line Items]
Total Revenues	85	74	55
Camzyos
Revenue from External Customer [Line Items]
Total Revenues	24	0	0
Sotyktu
Revenue from External Customer [Line Items]
Total Revenues	8	0	0
Revlimid
Revenue from External Customer [Line Items]
Total Revenues	9,978	12,821	12,106
Abraxane
Revenue from External Customer [Line Items]
Total Revenues	$ 811	$ 1,181	$ 1,247