REVENUE - Disaggregation of Revenue (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Total Revenues	$ 46,159	$ 46,385	$ 42,518
Net product sales
Disaggregation of Revenue [Line Items]
Total Revenues	44,671	45,055	41,321
Alliance revenues
Disaggregation of Revenue [Line Items]
Total Revenues	742	716	615
Other revenues
Disaggregation of Revenue [Line Items]
Total Revenues	$ 746	$ 614	$ 582