Revenue - Disaggregation of Revenue by Product and Region (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue from External Customer [Line Items]
Total Revenues	$ 11,887	$ 11,703	$ 23,535	$ 22,776
Performance obligation satisfied in previous period	184	146	331	430
United States
Revenue from External Customer [Line Items]
Total Revenues	8,268	7,388	15,962	14,398
Other Region
Revenue from External Customer [Line Items]
Total Revenues	192	191	419	355
International
Revenue from External Customer [Line Items]
Total Revenues	3,427	4,124	7,154	8,023
Eliquis
Revenue from External Customer [Line Items]
Total Revenues	3,235	2,792	6,446	5,678
Opdivo
Revenue from External Customer [Line Items]
Total Revenues	2,063	1,910	3,986	3,630
Pomalyst/Imnovid
Revenue from External Customer [Line Items]
Total Revenues	908	854	1,734	1,627
Orencia
Revenue from External Customer [Line Items]
Total Revenues	876	814	1,668	1,572
Sprycel
Revenue from External Customer [Line Items]
Total Revenues	544	541	1,027	1,011
Yervoy
Revenue from External Customer [Line Items]
Total Revenues	525	510	1,040	966
Empliciti
Revenue from External Customer [Line Items]
Total Revenues	77	86	152	171
Mature and other products
Revenue from External Customer [Line Items]
Total Revenues	435	473	897	979
Reblozyl
Revenue from External Customer [Line Items]
Total Revenues	172	128	328	240
Abecma
Revenue from External Customer [Line Items]
Total Revenues	89	24	156	24
Zeposia
Revenue from External Customer [Line Items]
Total Revenues	66	28	102	46
Breyanzi
Revenue from External Customer [Line Items]
Total Revenues	39	17	83	17
Inrebic
Revenue from External Customer [Line Items]
Total Revenues	23	16	41	32
Onureg
Revenue from External Customer [Line Items]
Total Revenues	32	12	55	27
Opdualag
Revenue from External Customer [Line Items]
Total Revenues	58	0	64	0
Camzyos
Revenue from External Customer [Line Items]
Total Revenues	3	0	3	0
Revlimid
Revenue from External Customer [Line Items]
Total Revenues	2,501	3,202	5,298	6,146
Abraxane
Revenue from External Customer [Line Items]
Total Revenues	$ 241	$ 296	$ 455	$ 610