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Revenue (Tables)
3 Months Ended
Mar. 31, 2022
Revenue from Contract with Customer [Abstract]  
Disaggregation of Revenue
The following table summarizes the disaggregation of revenue by nature:
Three Months Ended March 31,
Dollars in Millions20222021
Net product sales$11,308 $10,798 
Alliance revenues188 142 
Other revenues152 133 
Total Revenues$11,648 $11,073 
Revenue Recognition Gross-To-Net Adjustments
The following table summarizes GTN adjustments:
Three Months Ended March 31,
Dollars in Millions20222021
Gross product sales$16,650 $15,559 
GTN adjustments(a)
Charge-backs and cash discounts(1,763)(1,586)
Medicaid and Medicare rebates(2,084)(1,718)
Other rebates, returns, discounts and adjustments(1,495)(1,457)
Total GTN adjustments(5,342)(4,761)
Net product sales$11,308 $10,798 
(a)    Includes adjustments for provisions for product sales made in prior periods resulting from changes in estimates of $74 million and $217 million for the three months ended March 31, 2022, and 2021, respectively.
Revenue from External Customers by Products and Services
The following table summarizes the disaggregation of revenue by product and region:
Three Months Ended March 31,
Dollars in Millions20222021
In-Line Products
Eliquis$3,211 $2,886 
Opdivo1,923 1,720 
Pomalyst/Imnovid826 773 
Orencia792 758 
Sprycel483 470 
Yervoy515 456 
Empliciti75 85 
Mature and other products462 506 
New Product Portfolio
Reblozyl156 112 
Abecma67 — 
Zeposia36 18 
Breyanzi44 — 
Inrebic18 16 
Onureg23 15 
Opdualag— 
Recent LOE Products(a)
Revlimid2,797 2,944 
Abraxane214 314 
Total Revenues$11,648 $11,073 
United States$7,694 $7,010 
Europe2,413 2,553 
Rest of the World1,314 1,346 
Other(b)
227 164 
Total Revenues$11,648 $11,073 
(a)    Recent LOE Products includes products with significant decline in revenue from the prior reporting period as a result of a loss of exclusivity.
(b)    Other revenues include royalties and alliance-related revenues for products not sold by BMS’s regional commercial organizations.