Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2023

Accounting Policies [Abstract]

Estimated Useful Life of Asset

Depreciation is recognized using the straight-line method based on an estimated useful life of the asset, which is as follows:

Computer equipment	3 years
Laboratory equipment and office furniture	3 years
Leasehold improvement	Shorter of life of asset or lease term

Computation of Net Loss Per Share

Net loss per share was computed as follows (in thousands, except per share amounts):

	Year Ended December 31,
	2023		2022		2021
Numerator:
Net loss	$	(142,375)	$	(162,667)	$	(120,335)
Denominator:
Weighted average number of shares used in calculating net loss per share—basic and diluted	82,496		79,950		77,085
Net loss per share—basic and diluted	$	(1.73)	$	(2.03)	$	(1.56)

Potentially Dilutive Securities Not Included in Diluted Per Share Calculations

Potentially dilutive securities that were not included in the diluted per share calculations because they would be anti-dilutive were as follows (in thousands):

	Year Ended December 31,
	2023	2022	2021
Options to purchase common stock	12,990	14,215	10,485
Shares committed under the ESPP	1,337	1,222	390
Shares subject to RSUs	622	—	—
Total	14,949	15,437	10,875