Research Collaboration and License Agreements - Schedule of Milestone Payments by Indications (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2022 USD ($)
Proof-Of-Concept Trial, CVM Research
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	$ 10,000
First Indication | Proof-Of-Concept Trial, CVM Research
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	10,000
First Indication | Proof-Of-Concept Trial, B7H4 Research Program
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	10,000
Second Indication | Proof-Of-Concept Trial, CVM Research
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	0
Second Indication | Proof-Of-Concept Trial, B7H4 Research Program
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	0
Third Indication | Proof-Of-Concept Trial, CVM Research
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	0
Third Indication | Proof-Of-Concept Trial, B7H4 Research Program
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	0
Collaboration Agreement
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	371,250
Collaboration Agreement | United States
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	168,750
Collaboration Agreement | European Union
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	135,000
Collaboration Agreement | Japan
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	67,500
Collaboration Agreement | First Indication
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	165,000
Collaboration Agreement | First Indication | Phase 3 Clinical Event
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	35,000
Collaboration Agreement | First Indication | United States
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	75,000
Collaboration Agreement | First Indication | European Union
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	60,000
Collaboration Agreement | First Indication | Japan
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	30,000
Collaboration Agreement | Second Indication
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	123,750
Collaboration Agreement | Second Indication | Phase 3 Clinical Event
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	25,250
Collaboration Agreement | Second Indication | United States
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	56,250
Collaboration Agreement | Second Indication | European Union
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	45,000
Collaboration Agreement | Second Indication | Japan
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	22,500
Collaboration Agreement | Third Indication
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	82,500
Collaboration Agreement | Third Indication | Phase 3 Clinical Event
Collaborative Arrangement [Line Items]
Milestone payment for potential achievement of certain clinical development events	17,500
Collaboration Agreement | Third Indication | United States
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	37,500
Collaboration Agreement | Third Indication | European Union
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	30,000
Collaboration Agreement | Third Indication | Japan
Collaborative Arrangement [Line Items]
Milestone payments in connection with potential achievement of certain regulatory events	$ 15,000