CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 109,872	$ 151,795	[1]
Short-term marketable securities	219,960	214,458	[1]
Related party receivable from collaboration	103	4,945	[1]
Prepaid expenses and other current assets	7,687	8,082	[1]
Total current assets	337,622	379,280	[1]
Property and equipment, net	9,436	10,071	[1]
Operating lease right-of-use asset	3,570	4,045
Restricted cash	1,499	1,499	[1]
Other non-current assets	7,646	7,492	[1]
Total assets	359,773	402,387	[1]
Current liabilities:
Accounts payable	4,815	5,246	[1]
Accrued liabilities	29,478	33,258	[1]
Operating lease liability, current	5,153	5,077
Contract liabilities	5,117	17,774	[1]
Total current liabilities	44,563	61,355	[1]
Operating lease liability, non-current	4,073	5,385	[1]
Total liabilities	48,636	66,740	[1]
Commitments and contingencies			[1]
Stockholders' equity:
Preferred stock, $0.001 par value; 10,000 shares authorized; no shares issued or outstanding as of March 31, 2022 and December 31, 2021, respectively	0	0	[1]
Common stock, $0.001 par value; 400,000 shares authorized; 78,087 and 77,962 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively	78	78	[1]
Additional paid-in capital	763,152	754,664	[1]
Accumulated other comprehensive loss	(677)	(129)	[1]
Accumulated deficit	(451,416)	(418,966)	[1]
Total stockholders' equity	311,137	335,647	[1]
Total liabilities and stockholders' equity	$ 359,773	$ 402,387	[1]

[1] The condensed consolidated balance sheet as of December 31, 2021 has been derived from the audited financial statements as of that date.