Consolidated Statement of Stockholders' Equity (Deficit) - USD ($)	Total	Common Stock	Series A Preferred Stock	Additional Paid-in Capital	Accumulated Deficit
Balance at Dec. 31, 2017	$ 3,511,564	$ 41,529	$ 0	$ 107,760,036	$ (104,290,001)
Beginning balance (in shares) at Dec. 31, 2017		41,529,181	0
Issuance of common stock	16,120,312	$ 14,614		16,105,698
Issuance of common stock (in shares)		14,614,500
Stock options and warrants exercised	90,065	$ 45		90,020
Stock options and warrants exercised (in shares)		44,643
Exchange offer - 2017 Warrants deemed dividend	0			765,179	(765,179)
Exchange offer - 2017 Warrants	0	$ 1,969		(1,969)
Exchange offer - 2017 Warrants (in shares)		1,968,736
Conversion of accounts payable	298,350	$ 114		298,236
Conversion of accounts payable ( in shares)		113,874
Stock-based compensation	1,059,582			1,059,582
Net loss from operations	(36,502,316)				(36,502,316)
Ending Balance at Dec. 31, 2018	(15,422,443)	$ 58,271	$ 0	126,076,782	(141,557,496)
Ending balance (in shares) at Dec. 31, 2018		58,270,934	0
Issuance of common stock	5,928,235	$ 7,184		5,921,051
Issuance of common stock (in shares)		7,183,488
Stock options and warrants exercised	35,306	$ 630		34,676
Stock options and warrants exercised (in shares)		630,141
Reclassification of warrants to equity	857,072			857,072
Deemed dividend		$ 116		86,091	(86,207)
Deemed dividend (in shares)		116,496
Value of warrants issued with Series B Preferred Stock	6,709,961			6,709,961
Value of warrants issued with Convertible Note	430,000			430,000
Common stock issued for preferred stock dividend (in shares)		718,755
Preferred Stock Dividends, Common Stock Issued, Value	1,166,771	$ 719		1,166,052
Conversion of 4.5% convertible notes (in shares)		185,186
Conversion of Convertible Note	564,817	$ 185		564,632
Stock-based compensation	1,979,998			1,979,998
Net loss from operations	(37,162,827)				(37,162,827)
Ending Balance at Dec. 31, 2019	$ (34,913,110)	$ 67,105	$ 0	$ 143,826,315	$ (178,806,530)
Ending balance (in shares) at Dec. 31, 2019		67,105,000	0