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LICENSES AND AGREEMENTS (Details)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 21 Months Ended
May 07, 2018
USD ($)
Apr. 17, 2017
USD ($)
Jun. 28, 2014
USD ($)
Oct. 31, 2022
item
Aug. 31, 2021
USD ($)
Nov. 30, 2016
item
Aug. 31, 2011
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2022
USD ($)
Research and development               $ 72,502 $ 65,355 $ 214,208 $ 183,423      
Strategic Alliance Agreement                            
Research and development               100 100 100 200      
Research Collaboration And Clinical Grant Agreements With Moffitt                            
Research and development                   100        
Maximum | Strategic Alliance Agreement                            
Research and development arrangement, contract to perform for others, costs incurred, gross   $ 14,200                        
Sponsored research agreement                            
Research and development               300 300 500 300      
Second license agreement                            
Research and development                   100 100      
First WuXi Manufacturing and Services Agreement                            
Agreement term           3 years                
Research and development               3,400 4,500 10,600 12,700      
Number Of Statements Of Work | item           1                
Number Of Suites Under The Agreement | item           2                
Second WuXi Manufacturing and Services Agreement                            
Agreement term       3 years                    
Number Of Suites Under The Agreement | item       2                    
Termination notice period       120 days                    
Post regulatory before the termination date       15 months                    
Research and development | Strategic Alliance Agreement                            
Research and development arrangement, contract to perform for others, costs incurred, gross                   7,000        
Cooperative Research and Development Agreement                            
Agreement term         3 years   5 years              
Research and development         $ 500     500 500 1,500 1,500      
Notification Period To Terminate Agreement         60 days                  
Moffitt License Agreement One                            
Agreement term     20 years                      
Research and development               0 0 0 0      
Moffitt License Agreement One | Research and development                            
Payments for upfront licensing fee     $ 100                      
Moffitt License Agreement Two                            
Payments for upfront licensing fee $ 100                          
Additional milestone payable               400   400       $ 400
Moffitt License Agreement Two, Amended and Restated                            
Payments for upfront licensing fee                       $ 200    
Cellectis S.A                            
Research and development               100 100         $ 300
Novartis Pharma AG - License Agreement                            
Research and development               $ 0 $ 0 $ 0 $ 0   $ 10,000