STOCKHOLDERS' EQUITY - Stock based expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Total stock-based compensation expenses	$ 19,780	$ 19,306	$ 64,513	$ 50,661
Research and development
Total stock-based compensation expenses	11,272	11,504	38,863	29,291
General and administrative
Total stock-based compensation expenses	$ 8,508	$ 7,802	$ 25,650	$ 21,370