Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current Assets
Cash and cash equivalents	$ 118,366	$ 78,229
Short-term investments	241,807	426,181
Prepaid expenses and other assets	9,711	3,546
Total Current Assets	369,884	507,956
Property and equipment, net	100,746	100,938
Operating lease right-of-use assets	68,268	68,983
Long-term investments	0	91,588
Restricted cash	6,430	6,084
Long-term assets	596	1,784
Total Assets	545,924	777,333
Current Liabilities
Accounts payable	24,255	27,377
Accrued expenses	47,819	56,766
Operating lease liabilities	7,171	5,057
Total Current Liabilities	79,245	89,200
Non-Current Liabilities
Operating lease liabilities - non-current	71,943	65,474
Long-term note payable	1,000	1,000
Total Non-Current Liabilities	72,943	66,474
Total Liabilities	152,188	155,674
Commitments and contingencies
Stockholders' Equity
Common stock, $0.000041666 par value; 300,000,000 shares authorized, 157,840,581 and 157,004,742 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively	7	7
Accumulated other comprehensive loss	(2,038)	(601)
Additional paid-in capital	1,858,783	1,794,695
Accumulated deficit	(1,463,019)	(1,172,445)
Total Stockholders' Equity	393,736	621,659
Total Liabilities and Stockholders' Equity	545,924	777,333
Series A Convertible Preferred Stock
Stockholders' Equity
Preferred stock, Value	0	0
Series B Convertible Preferred Stock
Stockholders' Equity
Preferred stock, Value	$ 3	$ 3