X0508 4 2025-06-05 0 0001425205 IOVANCE BIOTHERAPEUTICS, INC. IOVA 0002055001 Kirby Daniel Gordon C/O IOVANCE BIOTHERAPEUTICS, INC. 825 INDUSTRIAL ROAD, SUITE 100 SAN CARLOS CA 94070 0 1 0 0 Chief Commercial Officer 0 Common Stock 2025-06-05 4 P 0 30000 1.84 A 30000 D Shares were acquired in the open market during a permitted trading window in accordance with the Issuer's Insider Trading Policy. A copy of the Insider Trading Policy is filed as Exhibit 19.1 to the Issuer's Annual Report on Form 10-K for the year ended December 31, 2024. /s/ Daniel Gordon Kirby 2025-06-06