144 0001363984 XXXXXXXX LIVE 0001425205 IOVANCE BIOTHERAPEUTICS, INC. 001-36860 825 Industrial Road, Suite 400 San Carlos CA 94070 650-260-7120 Maynard Ryan D Director Common Morgan Stanley Smith Barney LLC Executive Services

200 W Civic Center Dr, 4th Floor Sandy UT 84070

50000 503103.83 304794080 11/12/2024 NASDAQ Common 11/12/2024 Stock Option (right to buy) Iovance Biotherapeutics, Inc. N 50000 11/12/2024 Cash Y Exercise and sale of expiring options 11/12/2024 /s/ Ryan Maynard