X0306 4 2016-01-04 0 0001423824 ALDER BIOPHARMACEUTICALS INC ALDR 0001604874 Latham John A 11804 NORTH CREEK PARKWAY SOUTH BOTHELL WA 98011 0 1 0 0 Chief Scientific Officer Common Stock 2016-01-04 4 M 0 10000 1.265 A 251726 D Common Stock 2016-01-04 4 S 0 6500 31.0918 D 245226 D Common Stock 2016-01-04 4 S 0 3500 32.0115 D 241726 D Stock Option (Right to Buy) 1.265 2016-01-04 4 M 0 10000 0.00 D 2017-11-13 Common Stock 10000 30909 D The exercise of options reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2015. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 3, 2015. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.63 to $31.58, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote 3 to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $31.70 to $32.36, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote 4 to this Form 4. The option is fully vested. /s/ John A. Latham 2016-01-06