Balance Sheet Detail - Summary of Current Accrued Expenses (Detail) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Accrued Liabilities, Current [Abstract]
Accrued clinical trial research and development expenses	$ 3,642	$ 2,619
Accrued other research and development expenses	4,604	5,341
Accrued compensation and benefits	5,942	7,923
Accounts payable and other accrued expenses	1,395	4,309
Total accounts payable and accrued expenses	$ 15,583	$ 20,192