Condensed Balance Sheets (Unaudited) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 33,832	$ 90,672
Short-term investments	446,243	427,288
Prepaid expenses and other current assets	6,959	4,329
Total current assets	487,034	522,289
Property and equipment, net	2,567	2,673
Restricted cash	210	210
Operating lease right-of-use assets	5,149	5,573
Other long-term assets	3,625	3,306
Total assets	498,585	534,051
Current liabilities:
Accounts payable	1,337	3,236
Accrued expenses	14,112	16,956
Current operating lease liabilities	2,276	2,263
Total current liabilities	17,725	22,455
Long-term operating lease liabilities	4,114	4,612
Other long-term liabilities	496	375
Total liabilities	22,335	27,442
Stockholders' equity:
Preferred stock, $0.0001 par value; 10,000 shares authorized; no shares issued and outstanding
Common stock, $0.0001 par value; 200,000 shares authorized; 66,636 and 66,572 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively	7	7
Additional paid-in capital	948,312	941,359
Accumulated other comprehensive income (loss)	(6,648)	(1,789)
Accumulated deficit	(465,421)	(432,968)
Total stockholders' equity	476,250	506,609
Total liabilities and stockholders' equity	$ 498,585	$ 534,051