Consolidated Statements of Operations and Comprehensive Loss - USD ($)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Total revenue	$ 25,983,000	$ 24,354,000
Operating expenses
Selling, general and administrative	36,749,000	44,549,000
Research and development	51,030,000	48,929,000
Restructuring charges	2,638,000	0
Cost of goods sold	3,024,000	2,809,000
Total operating expenses	93,441,000	96,287,000
Loss from operations	(67,458,000)	(71,933,000)
Other income (expense)
Foreign exchange loss	(4,000)	(1,000)
Interest income	3,925,000	6,400,000
Interest expense	(154,000)	(231,000)
Total other income (expense), net	3,767,000	6,168,000
Loss before income tax expense	(63,691,000)	(65,765,000)
Income tax expense	0	0
Net loss	(63,691,000)	(65,765,000)
Other comprehensive loss:
Unrealized (loss) income on available-for-sale debt securities	(11,000)	142,000
Comprehensive loss	$ (63,702,000)	$ (65,623,000)
Net loss per share, basic (in dollars per share)	$ (2.36)	$ (2.44)
Net loss per share, diluted (in dollars per share)	$ (2.36)	$ (2.44)
Weighted average number of common shares outstanding, basic (in shares)	27,029,942	26,917,967
Weighted average number of common shares outstanding, diluted (in shares)	27,029,942	26,917,967
Product sales, net
Total revenue	$ 25,983,000	$ 24,354,000