Share-Based Compensation - Summary of Stock Option Activity (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Shares
Shares, Outstanding at beginning balance (in shares)	1,749,876
Shares, Granted (in shares)	1,583,038
Shares, Exercised (in shares)	(132,084)
Shares, Expired/cancelled (in shares)	(210,407)
Shares, Outstanding at ending balance (in shares)	2,990,423	1,749,876
Shares, Options exercisable (in shares)	722,198
Weighted Average Exercise Price
Weighted Average Exercise Price, Outstanding at beginning balance (in dollars per share)	$ 20.71
Weighted Average Exercise Price, Granted (in dollars per share)	15.28
Weighted Average Exercise Price, Exercised (in dollars per share)	3.04
Weighted Average Exercise Price, Expired/cancelled (in dollars per share)	20.61
Weighted Average Exercise Price, Outstanding at ending balance (in dollars per share)	19.28	$ 20.71
Weighted Average Exercise Price, Options exercisable (in dollars per share)	$ 18.53
Weighted Average Remaining Contractual Term, Outstanding	8 years 7 months 2 days	8 years 5 months 23 days
Weighted Average Remaining Contractual Term, Options exercisable	6 years 10 months 2 days
Aggregate Intrinsic Value, Outstanding	$ 2,849	$ 10,007
Aggregate Intrinsic Value, Options exercisable	$ 2,251
Shares, Vested and expected to vest	2,990,423
Weighted Average Exercise Price, Vested and expected to vest (in dollars per share)	$ 19.28
Weighted Average Remaining Contractual Term, Vested and expected to vest	8 years 7 months 2 days
Aggregate Intrinsic Value, Vested and expected to vest	$ 2,849