License Agreements - Additional Information (Detail) - USD ($)			1 Months Ended		3 Months Ended			12 Months Ended
	Nov. 22, 2021	Aug. 30, 2021	Jan. 31, 2021	Dec. 31, 2020	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2020	Dec. 31, 2021
License Agreement [Line Items]
Payable to licensor					$ 5,757,000			$ 5,757,000
Revenue					2,307,000	$ 120,000
Celgene License Agreement [Member]
License Agreement [Line Items]
Payments related to milestone					0	$ 0
Royalties were accrued on product sales					200,000
License fees, amount paid		$ 5,800,000
License fees, percentage of previously outstanding payment obligation		50.00%
Payable to licensor		$ 5,800,000
License agreement, balloon payment interest rate per annum		4.00%
Celgene License Agreement [Member] | EOC Pharma (Hong Kong) Limited [Member]
License Agreement [Line Items]
License fees, amount paid					$ 200,000
Payable to licensor				$ 2,800,000			$ 2,800,000	$ 200,000
Sublicense fees, percentage			20.00%					20.00%
License expense							$ 2,800,000	$ 200,000
Revenue								1,000,000.0
EOC License Agreement [Member]
License Agreement [Line Items]
Right to terminate the agreement					120 days
Upfront payment			$ 14,000,000.0		$ 14,000,000.0
Amount of certain development, regulatory, and sales milestones payments eligible to receive under license agreement.					$ 257,000,000.0
Milestone revenue	$ 1,000,000.0
Milestone payment received								$ 1,000,000.0
EOC License Agreement [Member] | License [Member]
License Agreement [Line Items]
Revenue				$ 14,000,000.0
EOC License Agreement [Member] | EOC Pharma (Hong Kong) Limited [Member]
License Agreement [Line Items]
Payment received from license agreement			$ 14,000,000.0