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Income Taxes - Schedule of Reconciliation of Statutory Federal Income Tax (Detail)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Federal tax at statutory rate 21.00% 21.00%
State income tax, net of federal benefit 0.50% 2.50%
Nondeductible interest (0.10%) (4.90%)
Other permanent items 0.40% (1.60%)
Nondeductible impairment (13.80%)  
Research credit 0.90% 28.80%
Change in valuation allowance (8.90%) (45.70%)
Effective tax rate   0.10%