Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Deficit [Member]
Balance at Dec. 31, 2017	$ 17,435,489	$ 2,707	$ 125,995,438	$ (108,562,656)
Balance, Shares at Dec. 31, 2017		27,070,038
Issuance of restricted stock		$ 6	(6)
Issuance of restricted stock, Shares		60,000
Issuance of common stock upon exercise of stock options	21,992	$ 2	21,990
Issuance of common stock upon exercise of stock options, Shares		16,802
Forfeiture of restricted stock, Shares		(741)
Stock-based compensation expense	1,079,721		1,079,721
Net and comprehensive loss	(7,425,532)			(7,425,532)
Balance at Mar. 31, 2018	11,111,670	$ 2,715	127,097,143	(115,988,188)
Balance, Shares at Mar. 31, 2018		27,146,099
Balance at Dec. 31, 2017	17,435,489	$ 2,707	125,995,438	(108,562,656)
Balance, Shares at Dec. 31, 2017		27,070,038
Net and comprehensive loss	(1,878,046)
Balance at Sep. 30, 2018	66,517,116	$ 4,059	176,953,759	(110,440,702)
Balance, Shares at Sep. 30, 2018		40,588,004
Balance at Mar. 31, 2018	11,111,670	$ 2,715	127,097,143	(115,988,188)
Balance, Shares at Mar. 31, 2018		27,146,099
Issuance of common stock upon exercise of stock options	1,660		1,660
Issuance of common stock upon exercise of stock options, Shares		1,000
Issuance of common stock,net of issuance costs	41,905,312	$ 1,169	41,904,143
Issuance of common stock, net of issuance costs, Shares		11,688,000
Forfeiture of restricted stock, Shares		(1,592)
Stock-based compensation expense	877,757		877,757
Net and comprehensive loss	(5,989,992)			(5,989,992)
Balance at Jun. 30, 2018	47,906,407	$ 3,884	169,880,703	(121,978,180)
Balance, Shares at Jun. 30, 2018		38,833,507
Issuance of common stock upon exercise of stock options	53,104	$ 3	53,101
Issuance of common stock upon exercise of stock options, Shares		34,297
Issuance of common stock,net of issuance costs	6,213,715	$ 172	6,213,543
Issuance of common stock, net of issuance costs, Shares		1,720,200
Stock-based compensation expense	806,412		806,412
Net and comprehensive loss	11,537,478			11,537,478
Balance at Sep. 30, 2018	66,517,116	$ 4,059	176,953,759	(110,440,702)
Balance, Shares at Sep. 30, 2018		40,588,004
Balance at Dec. 31, 2018	58,666,575	$ 4,059	177,621,807	(118,959,291)
Balance, Shares at Dec. 31, 2018		40,588,004
Cumulative effect of change in accounting principle			5,717	(5,717)
Stock-based compensation expense	621,685		621,685
Net and comprehensive loss	(8,492,825)			(8,492,825)
Balance at Mar. 31, 2019	50,795,435	$ 4,059	178,249,209	(127,457,833)
Balance, Shares at Mar. 31, 2019		40,588,004
Balance at Dec. 31, 2018	58,666,575	$ 4,059	177,621,807	(118,959,291)
Balance, Shares at Dec. 31, 2018		40,588,004
Net and comprehensive loss	(18,824,371)
Balance at Sep. 30, 2019	41,714,449	$ 4,059	179,499,769	(137,789,379)
Balance, Shares at Sep. 30, 2019		40,588,004
Balance at Mar. 31, 2019	50,795,435	$ 4,059	178,249,209	(127,457,833)
Balance, Shares at Mar. 31, 2019		40,588,004
Stock-based compensation expense	604,661		604,661
Net and comprehensive loss	(5,683,616)			(5,683,616)
Balance at Jun. 30, 2019	45,716,480	$ 4,059	178,853,870	(133,141,449)
Balance, Shares at Jun. 30, 2019		40,588,004
Stock-based compensation expense	645,899		645,899
Net and comprehensive loss	(4,647,930)			(4,647,930)
Balance at Sep. 30, 2019	$ 41,714,449	$ 4,059	$ 179,499,769	$ (137,789,379)
Balance, Shares at Sep. 30, 2019		40,588,004