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Results (Details) - EUR (€)
€ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Condensed Financial Statements, Captions [Line Items]        
Net loss € (47,249) € (21,773) € (95,905) € (59,056)
Operating loss (44,367) (33,750) (97,610) (65,786)
Research and development expenditure € 94,372 € 81,680 177,567 151,444
G&A and S&M expenses     28,600 16,200
Net finance income (expense)     1,800 6,900
Effect of exchange rate differences on cash and cash equivalents     1,866 € 5,304
IPF program and other proprietary programs        
Condensed Financial Statements, Captions [Line Items]        
Increase in subcontracting costs classified as R&D expenses     € 10,200