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Share capital - History (Details) - EUR (€)
€ in Thousands
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
History of the share capital        
Aggregate number of shares after transaction 50,936,778 46,256,078 39,076,342 30,299,129
Aggregate share capital after transaction € 275,510 € 250,187 € 211,390 € 163,904
March 26, 2015        
History of the share capital        
Share capital increase warrants     € 3,092  
Number of shares issued     571,000  
May 19, 2015        
History of the share capital        
Share capital increase new shares     € 40,751  
Number of shares issued     7,532,000  
June 19, 2015        
History of the share capital        
Share capital increase warrants     € 2,659  
Number of shares issued     491,000  
September 25, 2015        
History of the share capital        
Share capital increase warrants     € 640  
Number of shares issued     118,000  
December 4, 2015        
History of the share capital        
Share capital increase warrants     € 344  
Number of shares issued     64,000  
January 19, 2016        
History of the share capital        
Share capital increase new shares   € 36,575    
Number of shares issued   6,761,000    
April 1, 2016        
History of the share capital        
Share capital increase warrants   € 668    
Number of shares issued   132,000    
May 19, 2016        
History of the share capital        
Share capital increase warrants   € 762    
Number of shares issued   141,000    
September 19, 2016        
History of the share capital        
Share capital increase warrants   € 326    
Number of shares issued   60,000    
November 28, 2016        
History of the share capital        
Share capital increase warrants   € 467    
Number of shares issued   86,000    
April 6, 2017        
History of the share capital        
Share capital increase warrants € 1,337      
Number of shares issued 247,000      
April 21, 2017        
History of the share capital        
Share capital increase new shares € 23,331      
Number of shares issued 4,313,000      
June 20, 2017        
History of the share capital        
Share capital increase warrants € 281      
Number of shares issued 52,000      
September 21, 2017        
History of the share capital        
Share capital increase warrants € 152      
Number of shares issued 28,000      
November 23, 2017        
History of the share capital        
Share capital increase warrants € 222      
Number of shares issued 41,000