Commitments and Contingencies - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended	3 Months Ended		12 Months Ended
	Mar. 31, 2018	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Feb. 28, 2010
Harvard and Dana-Farber Agreement [Member] | Therapeutic Product [Member]
Other Commitments [Line Items]
Aggregate milestones payments						$ 7,700
Harvard and Dana-Farber Agreement [Member] | Diagnostic Product [Member]
Other Commitments [Line Items]
Aggregate milestones payments						$ 700
Harvard and Dana-Farber Agreement [Member] | License [Member]
Other Commitments [Line Items]
Annual license maintenance fees				$ 35
Harvard and Dana-Farber Agreement [Member] | License and Maintenance [Member]
Other Commitments [Line Items]
Annual license maintenance fees		$ 9	$ 9		$ 110
MUSC Agreement [Member] | License [Member]
Other Commitments [Line Items]
Annual license maintenance fees		$ 0	$ 25
Vivarta Therapeutics LLC [Member]
Other Commitments [Line Items]
License fee on agreement effective date	$ 10,000
License fee on receipt of positive freedom to operate analysis from legal counsel	$ 40,000
Vivarta Therapeutics LLC [Member] | Common Stock [Member]
Other Commitments [Line Items]
Issuance of common stock warrant	75,000
Warrant per share	$ 0.12