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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0001209191-10-034149.txt : 20100615
<SEC-HEADER>0001209191-10-034149.hdr.sgml : 20100615
<ACCEPTANCE-DATETIME>20100615101449
ACCESSION NUMBER:		0001209191-10-034149
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100611
FILED AS OF DATE:		20100615
DATE AS OF CHANGE:		20100615

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			COURNOT ANTOINE
		CENTRAL INDEX KEY:			0001454421

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-52981
		FILM NUMBER:		10896504

	MAIL ADDRESS:	
		STREET 1:		C/O RESEARCH PHARMACEUTICAL SERVICES,INC
		STREET 2:		520 VIRGINIA DRIVE
		CITY:			FORT WASHINGTON
		STATE:			PA
		ZIP:			19034

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RESEARCH PHARMACEUTICAL SERVICES, INC.
		CENTRAL INDEX KEY:			0001420070
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				204322769
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		520 VIRGINIA DRIVE
		CITY:			FORT WASHINGTON
		STATE:			PA
		ZIP:			19034
		BUSINESS PHONE:		215-540-0700

	MAIL ADDRESS:	
		STREET 1:		520 VIRGINIA DRIVE
		CITY:			FORT WASHINGTON
		STATE:			PA
		ZIP:			19034
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>c02432_4x0.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-06-11</periodOfReport>

    <issuer>
        <issuerCik>0001420070</issuerCik>
        <issuerName>RESEARCH PHARMACEUTICAL SERVICES, INC.</issuerName>
        <issuerTradingSymbol>RPSE RPSW</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001454421</rptOwnerCik>
            <rptOwnerName>COURNOT ANTOINE</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O RESEARCH PHARMACEUTICAL SERVICES</rptOwnerStreet1>
            <rptOwnerStreet2>INC. 520 VIRGINIA DRIVE</rptOwnerStreet2>
            <rptOwnerCity>FORT WASHINGTON</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19034</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President European Operations</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-06-11</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>62300</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>5.65</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                    <footnoteId id="F3"/>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1435564</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By APA Research SARL</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">The Reporting Person is the Manager of APA Research SARL, which beneficially holds 1,435,564 shares of common stock of ReSearch Pharmaceutical Services, Inc.  The Reporting Person has disclaimed beneficial ownership of the shares held by APA Research SARL except to the extent of its proportionate beneficial ownership therein.</footnote>
        <footnote id="F2">Approximately 499,288 shares owned by APA Research SARL are in an escrow fund.  If no additional claims are made against the escrow fund, 50% of these shares will be released from the escrow fund on December 23, 2010, and 50% of these shares will be released from the escrow fund on December 23, 2011. The Reporting Person controls or shares voting control over these shares.</footnote>
        <footnote id="F3">62,300 shares are being released from the escrow fund pursuant to a claim against the escrow fund.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Steven Bell</signatureName>
        <signatureDate>2010-06-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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