ACCOUNTS PAYABLE AND ACCRUED EXPENSES (Details) - USD ($)	Jun. 30, 2016	Dec. 31, 2015
Accounts payable
Cinical and regulatory expenses	$ 320,473	$ 322,193
Legal expenses	290,053	242,384
Other vendors	1,134,818	959,333
Total accounts payable	1,745,344	1,523,910
Accrued interest payable, related parties	206,661	176,940
Accrued interest payable	1,646,991	1,586,472
Accrued expenses	362,928	201,506
Deferred salary	291,666	291,666
Total accounts payable and accrued expenses	$ 4,253,590	$ 3,780,494