Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Revenues
Product revenue, net	$ 24,589	$ 20,127
Type of Revenue [Extensible List]	Product [Member]	Product [Member]
Operating expenses
Cost of sales	$ 6,085	$ 2,276
Type of Cost, Good or Service [Extensible List]	Product [Member]	Product [Member]
Research and development	$ 14,047	$ 21,134
Selling, general and administrative	27,598	29,299
Total operating expenses	47,730	52,709
Loss from operations	(23,141)	(32,582)
Other (expense) income
Interest income	300	427
Interest expense	(5,189)	(4,721)
Other (expense) income	(526)	74
Total other (expense) income	(5,415)	(4,220)
Net loss	$ (28,556)	$ (36,802)
Net loss per common share, basic and diluted	$ (0.57)	$ (0.95)
Weighted average common shares outstanding, basic and diluted	49,841	38,553
Other comprehensive income (loss):
Unrealized gains (losses) from available-for-sale securities, net of tax of $0	$ 1	$ (56)
Total other comprehensive income (loss)	1	(56)
Comprehensive loss	$ (28,555)	$ (36,858)