XML 52 R42.htm IDEA: XBRL DOCUMENT v3.10.0.1
Inventory - Additional Information (Detail) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Inventory [Line Items]        
Research and development expense $ 13,094,000 $ 11,769,000 $ 24,645,000 $ 22,524,000
Inventory finished goods shelf life     24 months  
Write-downs to inventory     $ 0  
Product [Member] | United Kingdom Facility at Patheon UK Limited [Member]        
Inventory [Line Items]        
Cost of sales expense for fixed overhead costs     3,500,000  
ZILRETTA [Member]        
Inventory [Line Items]        
Research and development expense     $ 3,700,000