X0306 4 2020-01-03 0 0001419600 Flexion Therapeutics Inc FLXN 0001617236 Levine Mark S. C/O FLEXION THERAPEUTICS, INC. 10 MALL ROAD, SUITE 301 BURLINGTON MA 01803 0 1 0 0 General Counsel Common Stock 2020-01-03 4 S 0 3724 D 43487 D Sale of shares of common stock to cover tax withholding obligations associated with the vesting of restricted stock unit award granted to the Reporting Person on February 1, 2018 and March 1, 2019. The shares were sold at a range of prices between $19.74 and $19.82. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided. Includes 938 shares of Common Stock that were acquired by the Reporting Person on December 20, 2019 at $9.89 per share pursuant to the Issuer's Employee Stock Purchase Plan. /s/ Mark S. Levine 2020-01-07