X0206 3 2019-01-10 0 0001419600 Flexion Therapeutics Inc FLXN 0001764676 Willwerth Christina C/O FLEXION THERAPEUTICS, INC. 10 MALL ROAD, SUITE 301 BURLINGTON MA 01803 0 1 0 0 Chief Strategy Officer Common Stock 22419 D Stock Option (right to buy) 0.16 2019-09-23 Common Stock 8750 D Stock Option (right to buy) 2.52 2023-07-18 Common Stock 25830 D Stock Option (right to buy) 17.61 2024-03-02 Common Stock 32000 D Stock Option (right to buy) 22.91 2025-01-20 Common Stock 25000 D Stock Option (right to buy) 29.06 2025-03-18 Common Stock 5000 D Stock Option (right to buy) 18.20 2026-01-03 Common Stock 20000 D Stock Option (right to buy) 18.56 2026-12-19 Common Stock 25000 D Stock Option (right to buy) 22.31 2028-01-31 Common Stock 23333 D The stock option is fully vested and exercisable. 1/4 of the shares subject to the option vest one year after January 21, 2015, with 1/48th of the shares vesting monthly thereafter over the next 3 years. 1/4 of the shares subject to the option vest one year after March 19, 2015, with 1/48th of the shares vesting monthly thereafter over the next 3 years. 1/4 of the shares subject to the option vest one year after January 4, 2016, with 1/48th of the shares vesting monthly thereafter over the next 3 years. 1/4 of the shares subject to the option vest one year after December 20, 2016, with 1/48th of the shares vesting monthly thereafter over the next 3 years. 1/4 of the shares subject to the option vest on January 1, 2019, with 1/48th of the shares vesting monthly thereafter over the next 3 years. /s/ Mark S. Levine, Attorney-in-Fact 2019-01-22