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Consolidated Statements of Cash Flows - USD ($)
6 Months Ended 12 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Operating activities        
Net loss $ (2,209,585) $ (11,778,084) $ (21,029,214) $ (13,876,927)
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation 48 620 700 4,451
Interest expense 105,669
Amortization of prepaid expenses - related party 39,093 67,986
Debt discount amortization 1,392,103 415,653 2,098,665 623,101
Debt issuance costs amortization 153,680 147,151 300,831 661,617
Stock-based compensation 1,038,239 1,939,157 3,460,078 3,700,431
Options issued to consultants (2,444,369) 2,874,147 6,085,950
Warrants issued to consultants 100,930 497,003
Interest expense deducted from loan proceeds 1,889 1,889
Loss on disposal of assets (4,862) (4,862)
Shares issued for services 100,930 2,825,943
Shares to be issued for research & development services 1,823,077
Shares issued for Sygnal license 1,435,000 1,435,000
Changes in operating assets and liabilities:        
Prepaid expenses and other current assets (4,658) (29,203) 29,475 3,519
Deferred issuance costs (35,000) (185,000)
Other receivables - related party 75,000
Accounts payable and accrued expenses 172,181 294,890 73,336 194,463
Deferred compensation 100,000 41,667
Net cash (used in) operating activities (1,837,361) (4,553,895) (7,327,845) (3,545,783)
Investing activities        
Purchase of property and equipment (504)
Net cash (used in) investing activities (504)
Financing activities        
Proceeds from the exercise of warrants 1,250,000 1,250,000
Proceeds from the issuance of common stock 2,500,000 2,500,000
Proceeds from issuance of notes payable 2,000,000 1,883,111 3,083,111 2,000,000
Net cash provided by financing activities 2,000,000 5,633,111 6,833,111 2,000,000
Net (decrease) in cash 162,639 1,079,216 (494,734) (1,546,287)
Cash, beginning of year 620,375 1,115,109 1,115,109 2,661,396
Cash, end of year 783,014 2,194,325 620,375 1,115,109
Supplemental non-cash information        
Accounts payable paid through issuance of Common Shares 24,000
Shares issued in lieu of cash bonuses 135,265
Legal expenses paid through relief of related party receivable 75,000
Related Party Debt and accrued interest converted into Common Shares 3,852,771
Interest paid 436,192 360,306 751,306 544,708
Taxes paid $ 1,600 $ 1,600 $ 2,243 $ 8,840