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Loss per Share (Tables)
3 Months Ended
Mar. 31, 2022
Loss per Share [Abstract]  
Weighted Average Shares Outstanding Accordingly, warrants issued with a $0.01 per share exercise price, are included in weighted average shares outstanding as follows (shares in thousands):

   
Three Months Ended
 
   
March 31, 2022
   
March 31, 2021
 
Weighted average shares outstanding
           
Common shares
   
498,723
     
481,620
 
Common shares issuable assuming excercise of nominally priced warrants
   
26,691
     
36,871
 
Weighted average shares outstanding
   
525,414
     
518,491
 
Anti-dilutive Equity Securities Anti-dilutive equity securities consist of the following at March 31, 2022 and 2021, respectively (in thousands):

   
2022
   
2021
 
Common stock options
   
31,759
     
31,864
 
Common stock purchase warrants
   
183,435
     
142,266
 
Convertible notes payable
   
94,172
     
60,329
 
     
309,366
     
234,459