X0303 4 2009-04-05 0 0000859737 HOLOGIC INC HOLX 0001415965 Doran Howard JR 250 CAMPUS DRIVE MARLBOROUGH MA 01752 0 1 0 0 President, Diagnostic Products Non-Qualified Stock Option (right to buy) 14.87 2009-04-05 4 A 0 22796 A 2015-01-16 Common Stock 22796 22796 D Non-Qualified Stock Option (right to buy) 33.31 2009-04-05 4 D 0 44000 D 2015-01-16 Common Stock 44000 0 D The option becomes exercisable in four equal annual installments beginning April 5, 2010. On April 5, 2009, the Issuer canceled, pursuant to the Issuer's Option Exchange Program, a seven-year option granted to the Reporting Person on January 16, 2008 for 44,000 shares at $33.31 per share. In exchange, the Reporting Person received the option reported herein. The option provided for vesting in five equal annual installments beginning on January 16, 2009. On April 5, 2009, the Issuer canceled, pursuant to the Issuer's Option Exchange Program, an option granted to the Reporting Person on January 16, 2008. In exchange, the Reporting Person will receive a replacement option on April 5, 2009 for a lesser number of shares, having an exercise price equal to 110% of the market price of the underlying stock on the grant date. Mark J. Casey, Attorney-In-Fact for: Howard B. Doran, Jr. 2009-04-07