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Stock-Based Compensation (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Share-based Payment Arrangement, Noncash Expense [Abstract]        
Stock options and other incentive awards granted (in shares) 35,240 27,590 190,320 211,326
Stock-Based Compensation        
Allocated share-based compensation expense $ 2,295 $ 2,639 $ 7,083 $ 7,707
Unrecognized stock-based compensation cost, net of estimated forfeiture 10,100   10,100  
Research and development        
Stock-Based Compensation        
Allocated share-based compensation expense 110 162 352 503
Selling, general and administrative expenses        
Stock-Based Compensation        
Allocated share-based compensation expense $ 2,185 $ 2,477 $ 6,731 $ 7,204