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Stock-Based Compensation (Details 5) (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Stock-Based Compensation
Allocated share-based compensation expense	$ 14,585	$ 16,064	$ 13,546
Research and development expenses
Stock-Based Compensation
Allocated share-based compensation expense	2,755	2,411	3,579
Selling, general and administrative expenses
Stock-Based Compensation
Allocated share-based compensation expense	11,830	13,653	9,967
Non-Performance Based Stock Awards
Stock-Based Compensation
Unrecognized compensation expense	$ 33,000
Future forfeiture rate (as a percent)	2.40%
Period for recognition of compensation cost	2 years

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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