<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-12-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000008328</issuerCik>
        <issuerName>Applied Minerals, Inc.</issuerName>
        <issuerTradingSymbol>AMNL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001414860</rptOwnerCik>
            <rptOwnerName>IBS CAPITAL LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE INTERNATIONAL PLACE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3120</rptOwnerStreet2>
            <rptOwnerCity>BOSTON</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02110</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001415021</rptOwnerCik>
            <rptOwnerName>IBS TURNAROUND FUND (QP) (A LTD PARTNERSHIP)</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE INTERNATIONAL PLACE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3120</rptOwnerStreet2>
            <rptOwnerCity>BOSTON</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02110</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001448562</rptOwnerCik>
            <rptOwnerName>TAFT DAVID A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE INTERNATIONAL PLACE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 3120</rptOwnerStreet2>
            <rptOwnerCity>BOSTON</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02110</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2021-12-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1403000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.005</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>19033734</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2021-12-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3597000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.005</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>19033734</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>10% PIK-Election Convertible Note</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.34</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2021-12-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1</value>
                    <footnoteId id="F3"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F3"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2020-12-31</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F6"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <footnoteId id="F3"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1058778</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>10% PIK-Election Convertible Note</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.34</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2021-12-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1</value>
                    <footnoteId id="F3"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F3"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2020-12-31</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F6"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <footnoteId id="F3"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1058778</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>10% PIK-Election Convertible Note</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.34</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2021-12-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1</value>
                    <footnoteId id="F3"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F3"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2020-12-31</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F6"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <footnoteId id="F3"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1058778</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This Form 4 is being filed on behalf of IBS Capital LLC (&quot;IBS Capital&quot;), The IBS Turnaround Fund (QP), LP (the &quot;QP Fund&quot;), and David A. Taft (&quot;Taft&quot;) (IBS Capital, the QP Fund and Taft are each a &quot;Reporting Person&quot;), each of which has the same business address and may have a pecuniary interest in the securities reported herein. IBS Capital is the general partner of QP Fund and The IBS Turnaround Fund, LP (the &quot;LP Fund&quot;). IBS Capital is the investment manager of The IBS Opportunity Fund, Ltd. (the &quot;Opp. Fund&quot; together with the QP Fund and the LP Fund, the &quot;IBS Capital Funds&quot;). Taft is the president and a member of IBS Capital. Taft is no longer a director of the Issuer. As of the date of this filing, none of the LP Fund, the Opp. Fund, QP Fund, IBS Capital or David A. Taft will beneficially own in the aggregate at least 10% of the Issuer (based on the Issuer's 10-Q for the quarterly period ended 9/30/2021, which reports 204,736,762 outstanding common stock shares).</footnote>
        <footnote id="F2">This transaction is being reported as a result of private transactions in which the LP Fund and the QP Fund sold securities to a third-party purchaser (the &quot;Purchaser&quot;). The LP Fund sold 1,403,000 shares of common stock to the Purchaser and the QP Fund sold 3,597,000 shares of common stock to the Purchaser. These transactions were effected at the same time. As a result of these transactions the overall beneficial ownership of IBS Capital and David Taft decreased to 19,033,734 shares of common stock. Following the transactions 5,902,997 shares of common stock are owned by the LP Fund and 11,655,583 shares of common stock are owned by the QP Fund.</footnote>
        <footnote id="F3">The LP Fund sold $1,427,792 of principal under a 10% PIK-Election Convertible Note to the Purchaser for $57,111.68, which principal amount is convertible into 4,199,388 shares of common stock of the Issuer. The QP Fund sold $2,867,160 of principal under a 10% PIK-Election Convertible Note to the Purchaser for $114,686.40, which principal amount is convertible into 8,432,824 shares of common stock of the Issuer. The Opp. Fund sold $278,582 of principal under a 10% PIK-Election Convertible to the Purchaser for $11,143.28, which principal amount is convertible into 819,359 shares of common stock of the Issuer.</footnote>
        <footnote id="F4">As a result of the transactions described in FN 3 IBS Capital and Taft beneficially own derivative securities that are convertible into 1,058,778 shares of common stock of the Issuer. The LP Fund beneficially owns derivative securities that are convertible into 329,317 shares of common stock of the Issuer. The QP Fund beneficially owns derivative securities that are convertible into 665,060 shares of common stock of the Issuer. The Opp. Fund beneficially owns derivative securities that are convertible into 64,401 shares of common stock of the Issuer.</footnote>
        <footnote id="F5">The Reporting Persons each disclaim any beneficial ownership of the securities except to the extent of any pecuniary interest.</footnote>
        <footnote id="F6">At the noteholder's option, the amount outstanding under the notes described in Footnote 3 may be converted into common stock of the Issuer. The notes described in Footnote 3 mature on 5/1/2023.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ David A. Taft, President of IBS Capital LLC</signatureName>
        <signatureDate>2021-12-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ David A. Taft, President of IBS Capital LLC, the general partner of The IBS Turnaround Fund (QP) (A Limited Partnership)</signatureName>
        <signatureDate>2021-12-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ David A. Taft</signatureName>
        <signatureDate>2021-12-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
