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Acquisitions (Details)
£ / shares in Units, $ in Millions, £ in Billions, kr in Billions
3 Months Ended
Sep. 15, 2021
USD ($)
Sep. 15, 2021
DKK (kr)
Sep. 15, 2021
GBP (£)
Aug. 09, 2021
USD ($)
May 06, 2021
USD ($)
Dec. 31, 2021
USD ($)
Sep. 15, 2021
£ / shares
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Business Acquisition [Line Items]                  
Goodwill           $ 6,680   $ 5,964 $ 5,858
OtiTopic Inc Asset Acquisition                  
Business Acquisition [Line Items]                  
Asset acquisition, percentage of shares acquired       100.00%          
Asset acquisition, consideration transferred       $ 38          
Asset acquisition, contingent payment       13          
Asset acquisition, future additional contingent payments       25          
Pre-tax charge associated with asset acquisition       $ 51          
Preliminary purchase price allocation associated with business combinations                  
Business Acquisition [Line Items]                  
Interest acquired (as a percent)         100.00%        
Cash payment for business, net of cash acquired         $ 28        
Contingent consideration         $ 10        
Contingent payment target period         2 years        
Fertin Pharma                  
Business Acquisition [Line Items]                  
Interest acquired (as a percent) 100.00%                
Net purchase price $ 821 kr 5.2              
Cash payment for business combination 821                
Cash 24                
Current assets 69                
Noncurrent assets 228                
Goodwill 378                
Other intangible assets 245                
Current liabilities 44                
Increase (decrease) in goodwill           41      
Increase (decrease) in other intangible assets           (82)      
Decrease in deferred tax liabilities           21      
Increase in property plant and equipment           19      
Noncurrent liabilities 79                
Fertin Pharma | Cash Consideration                  
Business Acquisition [Line Items]                  
Net purchase price 580                
Fertin Pharma | Consideration For Payment To Settle Indebtedness                  
Business Acquisition [Line Items]                  
Net purchase price $ 241                
Fertin Pharma | Minimum                  
Business Acquisition [Line Items]                  
Acquired intangible assets, estimated useful life 8 years 8 years 8 years            
Fertin Pharma | Maximum                  
Business Acquisition [Line Items]                  
Acquired intangible assets, estimated useful life 19 years 19 years 19 years            
Vectura                  
Business Acquisition [Line Items]                  
Interest acquired (as a percent) 74.77%                
Net purchase price $ 1,384   £ 1.0            
Cash 136                
Current assets 89                
Noncurrent assets 67                
Goodwill 590                
Other intangible assets 719                
Current liabilities 100                
Increase (decrease) in goodwill           (115)      
Increase (decrease) in other intangible assets           73      
Decrease in deferred tax liabilities           $ 22      
Business acquisition, share price (in dollars per share) | £ / shares             £ 165    
Ownership percentage           100.00%      
Noncurrent liabilities $ 117                
Vectura | Minimum                  
Business Acquisition [Line Items]                  
Acquired intangible assets, estimated useful life 3 years 3 years 3 years            
Vectura | Maximum                  
Business Acquisition [Line Items]                  
Acquired intangible assets, estimated useful life 15 years 15 years 15 years