X0306 4 2018-05-29 0 0001624899 STERIS plc STE 0001413087 Rosebrough Walter M Jr C/O RUTHERFORD HOUSE, STEPHENSONS WAY CHADDESDEN DERBY X0 DE21 6LY UNITED KINGDOM 1 1 0 0 President & CEO Ordinary Shares, 10 pence par value 2018-05-29 4 S 0 10697 102.91 D 52573 D Ordinary Shares, 10 pence par value 2018-05-29 4 F 0 1626 103.97 D 50947 D Ordinary Shares, 10 pence par value 2018-05-30 4 F 0 2842 104.57 D 48105 D Ordinary Shares, 10 pence par value 2018-05-30 4 F 0 2211 104.57 D 45894 D Ordinary Shares, 10 pence par value 43806 I See Footnote Below. This represents the average sales price of the 10,697 shares sold in the open market. The actual sales prices ranged from $102.73 per share to $103.23 per share. The Reporting Person, upon request by the SEC staff, will provide full information regarding the number of shares sold at each of the separate sales prices 1,626 shares were withheld from the 3,625 restricted shares that vested on May 29, 2018. These 1,626 ordinary shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 3,625 ordinary shares were awarded to Mr. Rosebrough on August 10, 2015 as part of an award of 14,500 restricted shares. These vested shares were valued at the NYSE closing market price on May 29, 2018. The remaining restrictions on these ordinary shares lapse as follows: 3,625 on May 28, 2019. 2,842 shares were withheld from the 4,250 restricted shares that vested on May 30, 2018. These 2,842 ordinary shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 4,250 ordinary shares were awarded to Mr. Rosebrough on May 30, 2014 as part of an award of 17,000 restricted shares. These vested shares were valued at the NYSE closing market price on May 30, 2018. 2,211 shares were withheld from the 4,000 restricted shares that vested on May 30, 2018. These 2,211 ordinary shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 4,000 ordinary shares were awarded to Mr. Rosebrough on May 30, 2017 as part of an award of 16,000 restricted shares. These vested shares were valued at the NYSE closing market price on May 30, 2018. The remaining restrictions on these ordinary shares lapse as follows: 4,000 on May 30, 2019; 4,000 on May 30, 2020; and 4,000 on May 30, 2021. These 45,894 ordinary shares are held by the Reporting Person as Trustee of a revocable trust established for his benefit. 29,668 of these Ordinary Shares are restricted. The restrictions on the restricted Ordinary Shares lapse as follows: 4,681 on June 1, 2018; 3,625 on May 28, 2019; 4,000 on May 30, 2019; 4,681 on June 3, 2019; 4,681 on June 1, 2020; 4,000 on June 1, 2020 and 4,000 on June 1, 2021. These ordinary shares are held by the Reporting Person's Spouse as Trustee of a revocable trust established for her benefit. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2018-05-31