<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13D" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13D/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: MAK Capital Fund LP -->
          <cik>0001426156</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Ordinary Shares, no par value per share</securitiesClassTitle>
      <dateOfEvent>04/01/2026</dateOfEvent>
      <previouslyFiledFlag>false</previouslyFiledFlag>
      <issuerInfo>
        <issuerCIK>0001412558</issuerCIK>
        <issuerCusips>
          <issuerCusipNumber>30050E105</issuerCusipNumber>
        </issuerCusips>
        <issuerName>Evotec SE</issuerName>
        <address>
          <com:street1>Essener Bogen 7</com:street1>
          <com:city>Hamburg</com:city>
          <com:stateOrCountry>2M</com:stateOrCountry>
          <com:zipCode>22419</com:zipCode>
        </address>
      </issuerInfo>
      <authorizedPersons>
        <notificationInfo>
          <personName>David N. Smith, Jr.</personName>
          <personPhoneNum>212-486-3211</personPhoneNum>
          <personAddress>
            <com:street1>590 Madison Avenue</com:street1>
            <com:street2>31st Floor</com:street2>
            <com:city>New York</com:city>
            <com:stateOrCountry>NY</com:stateOrCountry>
            <com:zipCode>10022</com:zipCode>
          </personAddress>
        </notificationInfo>
      </authorizedPersons>
    </coverPageHeader>
    <reportingPersons>
      <reportingPersonInfo>
        <reportingPersonCIK>0001426156</reportingPersonCIK>
        <reportingPersonNoCIK>N</reportingPersonNoCIK>
        <reportingPersonName>MAK Capital Fund LP</reportingPersonName>
        <memberOfGroup>a</memberOfGroup>
        <fundType>WC</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>D0</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>12503512.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>12503512.00</sharedDispositivePower>
        <aggregateAmountOwned>12503512.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>7.0</percentOfClass>
        <typeOfReportingPerson>PN</typeOfReportingPerson>
        <commentContent>For item 13:

The calculation is based upon 177,877,782 Ordinary Shares (including Ordinary Shares in the form of American Depositary Shares, each representing one-half of one Ordinary Share), outstanding as of March 30, 2026, as reported by the Issuer on its website.</commentContent>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonCIK>0001385702</reportingPersonCIK>
        <reportingPersonNoCIK>N</reportingPersonNoCIK>
        <reportingPersonName>MAK Capital One L.L.C.</reportingPersonName>
        <memberOfGroup>a</memberOfGroup>
        <fundType>OO</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>DE</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>12503512.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>12503512.00</sharedDispositivePower>
        <aggregateAmountOwned>12503512.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>7.0</percentOfClass>
        <typeOfReportingPerson>IA</typeOfReportingPerson>
        <commentContent>For item 13:

The calculation is based upon 177,877,782 Ordinary Shares (including Ordinary Shares in the form of American Depositary Shares, each representing one-half of one Ordinary Share), outstanding as of March 30, 2026, as reported by the Issuer on its website.</commentContent>
      </reportingPersonInfo>
      <reportingPersonInfo>
        <reportingPersonCIK>0001426157</reportingPersonCIK>
        <reportingPersonNoCIK>N</reportingPersonNoCIK>
        <reportingPersonName>Michael A. Kaufman</reportingPersonName>
        <memberOfGroup>a</memberOfGroup>
        <fundType>OO</fundType>
        <legalProceedings>N</legalProceedings>
        <citizenshipOrOrganization>X1</citizenshipOrOrganization>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>12503512.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>12503512.00</sharedDispositivePower>
        <aggregateAmountOwned>12503512.00</aggregateAmountOwned>
        <isAggregateExcludeShares>N</isAggregateExcludeShares>
        <percentOfClass>7.0</percentOfClass>
        <typeOfReportingPerson>IN</typeOfReportingPerson>
        <commentContent>For item 13:

The calculation is based upon 177,877,782 Ordinary Shares (including Ordinary Shares in the form of American Depositary Shares, each representing one-half of one Ordinary Share), outstanding as of March 30, 2026, as reported by the Issuer on its website.</commentContent>
      </reportingPersonInfo>
    </reportingPersons>
    <items1To7>
      <item1>
        <securityTitle>Ordinary Shares, no par value per share</securityTitle>
        <issuerName>Evotec SE</issuerName>
        <issuerPrincipalAddress>
          <com:street1>Essener Bogen 7</com:street1>
          <com:city>Hamburg</com:city>
          <com:stateOrCountry>2M</com:stateOrCountry>
          <com:zipCode>22419</com:zipCode>
        </issuerPrincipalAddress>
      </item1>
      <item4>
        <transactionPurpose>SCHEDULE 13D A/1
Amendment 1

This Amendment 1 ("Amendment 1") of Schedule 13D is filed with respect to the ordinary shares, no par value per share (the "Shares") of EVOTEC SE (the "Issuer") beneficially owned by the MAK Capital Fund LP, a Bermuda limited partnership ("MAK Fund"), MAK Capital One L.L.C., a Delaware limited liability company ("MAK Capital"), as the investment manager of MAK Fund and Michael A. Kaufman, as Managing Member of MAK Capital (collectively with MAK Fund and MAK Capital, "MAK" and together MAK Fund and MAK Capital collectively the "Reporting Persons"), amends and supplements the Schedule 13D initially filed with the Securities and Exchange Commission (the "SEC") on March 30, 2026 the "Schedule 13D".

Except as set forth herein in this Amendment 1, the Schedule 13D is unmodified.

In furtherance of the Purpose of Transaction, the Reporting Persons sent a letter to the Issuer's Supervisory &amp; Management Board, which letter is attached as Exhibit 2 to this Amendment 1.</transactionPurpose>
      </item4>
      <item7>
        <filedExhibits>1. Transactions in Securities in the Last 60 Days, dated April 1, 2026.

2. April 2 Letter to the Supervisory Board and Management Board of Evotec SE

3. Joint Filing Agreement, dated March 30, 2026 is hereby incorporated by reference.</filedExhibits>
      </item7>
    </items1To7>
    <signatureInfo>
      <signaturePerson>
        <signatureReportingPerson>MAK Capital Fund LP</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael A. Kaufman</signature>
          <title>Managing Member</title>
          <date>04/06/2026</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>MAK Capital One L.L.C.</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael A. Kaufman</signature>
          <title>Managing Member</title>
          <date>04/06/2026</date>
        </signatureDetails>
      </signaturePerson>
      <signaturePerson>
        <signatureReportingPerson>Michael A. Kaufman</signatureReportingPerson>
        <signatureDetails>
          <signature>/s/ Michael A. Kaufman</signature>
          <title>Michael A. Kaufman</title>
          <date>04/06/2026</date>
        </signatureDetails>
      </signaturePerson>
    </signatureInfo>
  </formData>

</edgarSubmission>
