Commitments and Contingencies - Additional Information (Detail)		1 Months Ended	3 Months Ended	9 Months Ended
	Feb. 04, 2022 USD ($)	Dec. 31, 2013 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2022 USD ($) item	Sep. 30, 2021 USD ($)	Nov. 04, 2022 USD ($)	Sep. 05, 2022 USD ($)	Apr. 30, 2022 USD ($)	Feb. 28, 2022 USD ($)	Dec. 31, 2021 USD ($)	Jun. 30, 2021 USD ($)	Mar. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Commitments and Contingencies [Line Items]
Contract amount								$ 700,000	$ 200,000
Contractual amendment			$ 900,000	$ 900,000
Contractual obligation			3,500,000	3,500,000
Asset Retirement Obligations, Noncurrent			$ 282,000	$ 282,000						$ 0
Facility Lease Incremental Borrowing Rate			5.75%	5.75%
Right of use asset impairment			$ 322,000	$ 322,000	$ 0
Personal Service Agreement with Trauma Research LLC
Commitments and Contingencies [Line Items]
Contract amount	$ 250,000
Term of agreement	1 year
Contractual obligation							$ 21,000
Sponsored Research Agreement with Trauma Research, LLC
Commitments and Contingencies [Line Items]
Contract amount	$ 400,000
Forecast | Sponsored Research Agreement with Trauma Research, LLC
Commitments and Contingencies [Line Items]
Contractual obligation						$ 63,000
Newly Leased Office Space and Manufacturing Facility
Commitments and Contingencies [Line Items]
Non-cancellable operating lease period		125 months
Lease renewal term		60 months
Lease initial base rent per month		$ 23,000
Rent expense		$ 3,300,000
New CRO
Commitments and Contingencies [Line Items]
Contract amount													$ 1,400,000
Contractual deposit Commitment			315,000	315,000
Contractual obligation			100,000	100,000
Remaining unapplied deposit			200,000	$ 200,000
Intravenous treatment for COVID 19 patients
Commitments and Contingencies [Line Items]
Number of subjects under interim enrollment | item				35
Intravenous IV treatment for COVID 19 patients [Member]
Commitments and Contingencies [Line Items]
Contract amount													$ 1,800,000
Net Contractual Adjustment			500,000	$ 500,000
Contractual obligation			0	0
Revised contract amount			1,300,000	1,300,000
Regional Hospital Group, AP-018 Study
Commitments and Contingencies [Line Items]
Contract amount												$ 318,000
Contractual amendment												946,000
Contractual obligation			0	0								$ 1,300,000
Regional Hospital Group, AP-019 Study
Commitments and Contingencies [Line Items]
Contract amount											$ 2,600,000
Contractual obligation			$ 0	$ 0