Commitments and Contingencies - Additional Information (Detail)		1 Months Ended		6 Months Ended
	Feb. 04, 2022 USD ($)	Apr. 30, 2022 USD ($)	Dec. 31, 2013 USD ($)	Jun. 30, 2022 USD ($) item	Nov. 04, 2022 USD ($)	Sep. 05, 2022 USD ($)	Jun. 30, 2021 USD ($)	Mar. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Commitments and Contingencies [Line Items]
Contract amount		$ 700,000
Facility Lease Incremental Borrowing Rate				5.75%
Personal Service Agreement with Trauma Research LLC
Commitments and Contingencies [Line Items]
Contract amount	$ 250,000
Term of agreement	1 year
Contractual obligation				$ 125,000
Sponsored Research Agreement with Trauma Research, LLC
Commitments and Contingencies [Line Items]
Contract amount	$ 400,000
Contractual obligation				239,000
Minimum
Commitments and Contingencies [Line Items]
Expected completion period for contracts		3 months
Maximum
Commitments and Contingencies [Line Items]
Expected completion period for contracts		5 months
Forecast | Maximum | Personal Service Agreement with Trauma Research LLC
Commitments and Contingencies [Line Items]
Contractual obligation						$ 21,000
Forecast | Maximum | Sponsored Research Agreement with Trauma Research, LLC
Commitments and Contingencies [Line Items]
Contractual obligation					$ 62,000
Newly Leased Office Space and Manufacturing Facility
Commitments and Contingencies [Line Items]
Non-cancellable operating lease period			125 months
Lease renewal term			60 months
Lease initial base rent per month			$ 23,000
Rent expense			$ 3,300,000
New CRO
Commitments and Contingencies [Line Items]
Contract amount									$ 1,400,000
Contractual deposit Commitment				315,000
Contractual obligation				300,000
Remaining unapplied deposit				100,000
Intravenous treatment for COVID 19 patients
Commitments and Contingencies [Line Items]
Contract amount									1,800,000
Contractual deposit Commitment									$ 345,000
Contractual amendment				$ 500,000
Number of subjects under interim enrollment | item				35
Revised contract amount				$ 1,300,000
Regional Hospital Group, AP-018 Study
Commitments and Contingencies [Line Items]
Contract amount								$ 318,000
Contractual deposit Commitment								$ 105,000
Contractual amendment				1,000,000.0
Regional Hospital Group, AP-019 Study
Commitments and Contingencies [Line Items]
Contract amount							$ 2,500,000
Contractual deposit Commitment							$ 300,000
Contractual amendment				900,000
Contractual obligation				0
Remaining unapplied deposit				100,000
Revised contract amount				$ 3,400,000