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Going Concern - Additional Information (Detail) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Dec. 31, 2017
Cash and Cash Equivalents, at Carrying Value $ 5,160,070   $ 7,585,392  
Net Income (Loss) Attributable to Parent (5,811,634) $ 22,039,472    
Gain (Loss) on Derivative Instruments, Net, Pretax (3,159,532) 25,614,305    
Operating Expenses 2,675,867 3,574,833    
Net Cash Provided by (Used in) Operating Activities (2,440,218) (3,604,025)    
Retained Earnings (Accumulated Deficit) (176,814,142)   (171,002,508)  
Stockholders' deficit (467,983) (8,856,812) $ 5,236,096 $ (34,176,885)
Stock Issued During Period, Value, Stock Options Exercised   $ 400,759    
Cash requirements for fixed, on-going expenses such as payroll, legal and accounting, patents and overhead at an average cash burn rate 700,000      
Warrant to purchase shares of common stock [Member]        
Stock Issued During Period, Value, Stock Options Exercised $ 20,000