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Equity Instruments (Tables)

6 Months Ended

Jun. 30, 2016

Summary of Stock Options Outstanding and Exercisable

Stock options outstanding and exercisable at June 30, 2016 are summarized in the table below:


Range of Exercise Prices	Number of Options Outstanding and Exercisable		Weighted Average Exercise Price		Weighted Average Remaining Contractual Lives

$1.03 - $4.00		4,670,832	$	2.35	4.91
$4.01 - $7.00		1,240,000	$	6.17	5.39
$7.01 - $8.93		935,000	$	7.73	6.58

		6,845,832	$	3.78	5.23

Summary of Stock-Based Compensation Expense

The following table summarizes stock-based compensation expense for the three and six months ended June 30, 2016 and 2015:


	Three Months Ended June 30,				Six Months Ended June 30,
	2016		2015		2016		2015
Research and development expenses
Stock options	$	65,000	$	449,000	$	155,000	$	1,057,000

General and administrative expenses
Common stock issued for services		-		-		60,000		30,000
Stock options		208,000		1,192,000		728,000		1,729,000

	$	273,000	$	1,641,000	$	943,000	$	2,816,000


Unrecognized expense at June 30, 2016	$	555,407

Weighted average remaining years to vest		0.83

Warrants Issued in Conjunction with its Senior Convertible Debentures

Ampio issued warrants in conjunction with its senior convertible debentures, 2011 private placements and an underwritten public offering. A summary of all Ampio warrants is as follows:


	Number of Warrants		Weighted Average Exercise Price		Weighted Average Remaining Contractual Life

Outstanding December 31, 2015		499,076	$	3.24	1.19
Warrants exercised		-	$	-
Warrants expired		(500)	$	3.13

Outstanding June 30, 2016		498,576	$	3.24	0.79

Ampio [Member]

Assumptions Used in Computing Fair Value of All Options Granted

Ampio has computed the fair value of all options granted during the six months ended June 30, 2016 using the following assumptions:


Expected volatility			124%
Risk free interest rate			0.61%
Expected term (years)			1.0
Dividend yield			0.0%
Forfeiture rate			5.3%

Stock Option Activity

Ampio stock option activity is as follows:


	Number of Options		Weighted Average Exercise Price		Weighted Average Remaining Contractual Life
Outstanding December 31, 2015		7,315,832	$	3.71		6.58
Granted		5,000	$	6.53
Exercised		-	$	-
Forfeited		-	$	-
Expired or Cancelled		(475,000)	$	2.67

Outstanding June 30, 2016		6,845,832	$	3.78		5.23

Exercisable at June 30, 2016		6,490,935	$	3.77		5.04

Available for grant at June 30, 2016		3,441,647

- Definition

Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable.

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