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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001209191-09-054309.txt : 20091124
<SEC-HEADER>0001209191-09-054309.hdr.sgml : 20091124
<ACCEPTANCE-DATETIME>20091124193619
ACCESSION NUMBER:		0001209191-09-054309
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20091123
FILED AS OF DATE:		20091124
DATE AS OF CHANGE:		20091124

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blumenfeld S Morry
		CENTRAL INDEX KEY:			0001424202

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33966
		FILM NUMBER:		091206118

	MAIL ADDRESS:	
		STREET 1:		C/O MEDITECH ADVISORS LLC
		STREET 2:		11 KIRYAT HA'MADA,POB 45163, HAR HOTZVIM
		CITY:			JERUSALEM
		STATE:			L3
		ZIP:			91450

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MAKO Surgical Corp.
		CENTRAL INDEX KEY:			0001411861
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				201901148
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2555 DAVIE ROAD
		CITY:			FT. LAUDERDALE
		STATE:			FL
		ZIP:			33317
		BUSINESS PHONE:		954-927-2044

	MAIL ADDRESS:	
		STREET 1:		2555 DAVIE ROAD
		CITY:			FT. LAUDERDALE
		STATE:			FL
		ZIP:			33317
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2009-11-23</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001411861</issuerCik>
        <issuerName>MAKO Surgical Corp.</issuerName>
        <issuerTradingSymbol>MAKO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001424202</rptOwnerCik>
            <rptOwnerName>Blumenfeld S Morry</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>550 GRAND STREET</rptOwnerStreet1>
            <rptOwnerStreet2>APARTMENT J10H</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10002</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2009-11-23</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>67236</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>72147</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Meditech Advisors LLC</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Meditech Advisors LLC transferred 67,236 shares to Winton Capital Holdings Ltd. (&quot;Winton&quot;), which Meditech Advisors LLC was holding in trust for Winton.  In connection with this transfer, Meditech Advisors LLC retained 4,642 shares that were formerly held in trust for Winton.  The closing price of the stock on November 23, 2009 was $8.95.</footnote>
        <footnote id="F2">Please reference Footnote 1 above.</footnote>
        <footnote id="F3">The shares are owned by Meditech Advisors LLC, the partners of which are Eitan Machover, Samuel Cubac, Grosvenor LLC and Allandale Ltd. The reporting person and certain of his family members constitute the members of Grosvenor LLC. As such, the reporting person may be deemed to be an indirect beneficial owner of these shares, but he disclaims beneficial ownership of the shares except to the extent of his pecuniary interest therein.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Menashe R. Frank, attorney in fact</signatureName>
        <signatureDate>2009-11-24</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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